10 best anime to watch if you like Possibly the Greatest Alchemist of All Time

Since its 2025 premiere, Possibly the Greatest Alchemist of All Time has quickly become a fan-favorite anime series. The story of Takumi Iruma mastering alchemy to become an exceptionally skilled inventor in another world provides plenty of excitement and wish fulfillment.

With its captivating storytelling, powerful alchemy, and engaging characters, many viewers are looking for similar series to enjoy. Fortunately, many fantastic anime feature magic, action, adventure, and overpowered protagonists similar to Takumi of Possibly the Greatest Alchemist of All Time.

For fans who can't get enough of seeing Takumi use his alchemical skills to create amazing inventions or handle unexpected challenges, these 10 anime series will provide a similar thrill.

10 best anime for fans of Possibly the Greatest Alchemist of All Time

1) The Rising of the Shield Hero

The Rising of the Shield Hero (Image via Kinema Citrus)

The Rising of the Shield Hero features Naofumi Iwatani, who is summoned along with three others to a parallel world to serve as the Cardinal Heroes and defend against encroaching monster waves. Naofumi becomes the Shield Hero but finds himself ostracized and betrayed.

However, through his inner strength and the help of his demi-human companion, Raphtalia, Naofumi proves to be an incredibly resourceful hero capable of taking on anything despite only being armed with a shield. Like Takumi discovering his alchemical skills, Naofumi unlocks his shield's power through strategy.

Additionally, the series pulls no punches when it comes to dark story elements action-packed monster battles and displaying how far the main character can rise with enough determination. Any fan of Possibly the Greatest Alchemist of All Time will get invested in Naofumi's epic journey from zero to hero.

2) Wise Man's Grandchild

Wise Man's Grandchild (Image via Silver Link)

Wise Man's Grandchild is about another overpowered anime hero summoned from our world. The show follows Shin Wolford, an ordinary salaryman reborn and adopted in a magical new world by the powerful Merlin Wolford.

Shin inherits Merlin's magical abilities and regiment training from a young age, allowing him to become a veritable prodigy in all forms of combat and spellcasting by 15. Like Takumi's alchemy in Possibly the Greatest Alchemist of All Time, Shin effortlessly creates advanced magic and enchantments.

He enters a magic academy and continues to shake things up by advancing inventions centuries ahead of their time. For fans who have wondered what it would be like to see Takumi cut loose with his alchemy to shape the world around him, Shin gives a glimpse of that happening.

3) That Time I Got Reincarnated as a Slime

That Time I Got Reincarnated as a Slime (Image via 8bit)

For another fun isekai with skill mechanics and masterful world-building, That Time I Got Reincarnated as a Slime is a must-watch. When salaryman Satoru Mikami dies and is reborn as a slime monster, he discovers the unique ability to mimic the traits of anything he consumes.

Much like Takumi's varied alchemy, this gives Rimuru Tempest incredible flexibility in acquiring deadly new magic, skills like thought acceleration and the ability to form bonds with dragons and other powerful beings. What starts as a weak slime quickly grows in power, gaining followers and building a nation.

The innovative tactics and dominance over foes make Rimuru feel every bit as unstoppable as Takumi when he uses alchemy. Likewise, the lighthearted tone mixed with captivating world lore will appeal to any Possibly the Greatest Alchemist of All Time fan.

4) Mushoku Tensei: Jobless Reincarnation

Mushoku Tensei: Jobless Reincarnation (Image via Studio Bind)

Mushoku Tensei also tells the redemption story of a flawed man reborn into a fantasy world. NEET Rudeus Greyrat is tragically killed but gifted a second chance at a new life. He retains his intellectual maturity with an almost unprecedented aptitude for magic.

This ability allows the new Rudy to rapidly advance his magical and swordsmanship skills from a young age. Much like Takumi experimenting with alchemy, Rudy constantly innovates new applications of magic, from creating mist barriers to developing advanced magical spells.

Seeing him develop relationships, build his legend, fight against his inner demons, and explore the wider world makes for an exceptionally captivating isekai. Any fan of protagonist growth and magic in Possibly the Greatest Alchemist of All Time will love Mushoku Tensei.

5) Log Horizon

Log Horizon (Image via Satelight, Studio Deen)

Log Horizon stands out with rich game mechanics and world-building. It focuses on the brilliant, shrewd strategist Shiroe and his companions, navigating living permanently inside the expansive MMORPG Elder Tale following a mysterious update.

Shiroe's masterful understanding of game mechanics and abilities to form influential diplomatic ties allows him to tip situations heavily in his favor, similar to Takumi's alchemical feats in shaping his surroundings. Viewers discover deeper intricacies behind crafting, large-scale PVP warfare, and faction politics.

Like Possibly the Greatest Alchemist of All Time, the cerebral storytelling approach mixed with captivating game lore helps Log Horizon stand tall among fantasy anime.

6) The World's Finest Assassin Gets Reincarnated in Another World as an Aristocrat

The World's Finest Assassin Gets Reincarnated in Another World as an Aristocrat (Image via Silver Link, Studio Palette)

In a twist on the typical reincarnation premise, The World's Finest Assassin sends the world's deadliest assassin into a fantasy world on a mission. Reborn as Lugh Tuatha Dé, his peerless skills become supplemented with powerful magic as he aims to kill the hero destined to save the world. Lugh has exacting precision and a thirst for innovation regarding his abilities.

Much like Takumi's upturning expectations with his alchemy skills in Possibly the Greatest Alchemist of All Time, Lugh combines his masterful assassin techniques and custom magic to similarly shock opponents who underestimate him as just a child. Lugh's constant innovation also keeps it irresistibly entertaining.

7) Grimgar: Ashes and Illusions

Grimgar: Ashes and Illusions (Image via A-1 Pictures)

Unlike most trapped-in-a-game style series, Grimgar sets itself apart with its gritty realism, showcasing genuine struggle. It focuses on a group of amnesiac youths making ends meet by taking increasingly dangerous monster-hunting assignments.

They must regularly confront the brutal difficulties of living in this unfamiliar RPG-like world. Much like Takumi's early struggles mastering alchemy in Possibly the Greatest Alchemist of All Time, the protagonists of Grimgar must improve through teamwork, hard sacrifices, and steady growth.

The well-paced character development combined with a dark, lifelike take on the trapped fantasy genre makes Grimgar a refreshing change of pace.

8) Arifureta: From Commonplace to World's Strongest

Arifureta: From Commonplace to World's Strongest (Image via Asread, White Fox)

Arifureta tells the extreme redemption story of Hajime Nagumo. He begins as one of the weakest students at a magic academy before suddenly being summoned to a dangerous fantasy world.

Facing relentless and lethal monsters in the abyss, Hajime must endure agonizing trials and inventions to survive and escape. Emerging from his descent, Hajime utilizes alchemy-like transmutation and weapon creation to gain abilities surpassing any magician.

If fans wish to see how Takumi from Possibly the Greatest Alchemist of All Time might fare against rival alchemists or threats in all-out battles, Arifureta delivers with its unrelenting protagonist.

9) How a Realist Hero Rebuilt the Kingdom

How a Realist Hero Rebuilt the Kingdom (Image via J.C. Staff)

For a uniquely refreshing isekai angle, How a Realist Rebuilt the Kingdom sends Kazuya Souma into a monarch's body, tasked with saving his crumbling nation. With little magic capability, Kazuya relies on his extensive administrative and technological knowledge from Earth to institute calculated reforms.

Seeing Kazuya incorporate more scientific elements like crop rotation, electricity, and education system revamps feels akin to Takumi's innovative alchemy pushing development ahead in Possibly the Greatest Alchemist of All Time.

This series features an intelligent protagonist who relies more on his intellectual abilities rather than pure magical firepower. The strategic statecraft and resource management needed makes How a Realist Hero Rebuilt the Kingdom a thinking man's isekai.

10) Maoyu: Archenemy & Hero

Maoyu: Archenemy & Hero (Image via Arms)

Maoyu: Archenemy & Hero is another unique nation-building fantasy. Hero arrives to defeat the Demon Queen, but she shows him how united human kingdoms will just fight each other without a common enemy.

So, they join forces instead and use their powers to advance humanity. The two implement ideas like agriculture, economics, and education to rapidly progress society.

Maoyu shares the inventiveness of improving a medieval fantasy world through modern knowledge that Possibly the Greatest Alchemist of All Time executes so well. The romantic comedy element and eccentric characters also help make the economics engaging.

Conclusion

Possibly the Greatest Alchemist of All Time hits a perfect combination of escapist fantasy, OP protagonist, and magic systems mastery that leaves viewers wanting more. These 10 anime all capture aspects of the show that make it so bingeable.

Whether fans want more reincarnation journeys, overpowered MCs, alchemy, or nation-building, this list has covered recommendations for the next anime obsession. Viewers should prepare to lose some sleep as these shows can get addictive.

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Edited by Ivanna Lalsangzuali