10 Most powerful immortal anime villains, ranked

For a long time, viewers have been enthralled with immortal anime villains because of their endless power and unwavering presence. These characters defy the natural laws of life and death and bring a unique and often terrifying dynamic to their respective series.

To these characters, being one of the strongest immortal anime villains means more than just living forever; it often bestows a many otherworldly powers that render them unbeatable. The sources of their immortality are as diverse as their abilities, ranging from old curses to heavenly interventions.

This listicle will delve into the world of immortal anime villains, ranking the ten most powerful among them.

Disclaimer: The article reflects the views and opinions of the author.

10 Most powerful immortal anime villains in history, ranked

10) Hidan (Naruto)

Hidan's form after performing his ritual (Image via Studio Pierrot)

In the Naruto series, Hidan is a member of the notorious Akatsuki organization. His worship of the deity Jashin granted him immortality, which enabled him to survive fatal injuries and make him a formidable opponent in battle. His main ability is his ritualistic killing method, which involves using his own blood to create a link with his opponent. By inflicting wounds on himself, he can inflict the same wounds on his target, thereby turning himself into a living voodoo doll.

Hidan is a terrifying opponent due to his sadistic nature and immortality. However, he ranks lowest on this list of immortal anime villains due to his lack of versatility and reliance on particular conditions for his abilities. His defeat at the hands of Shikamaru Nara, who outsmarted him and buried him alive, highlights his vulnerabilities and the limitations of his immortality.

9) Zeref Dragneel (Fairy Tail)

Zeref as seen in the anime (Image via Satelite, A-1 Pictures)

Zeref Dragneel, the dark wizard from Fairy Tail, is one of the most tragic and complex immortal anime villains. Zeref's life is marked by loneliness and despair due to his curse of immortality and an array of destructive magic. He is fatally powerful, for everything he cares about meets its end due to his curse of Ankhseram. Zeref is a powerful opponent due to his extensive magical knowledge and immortality, allowing him to withstand harm.

Zeref can control life and death, summon strong demons, and perform ancient, forbidden magic. His most notable creation is the Etherious Natsu Dragneel (E.N.D), a demon designed to kill him. Zeref's emotional turmoil and eventual desire for death limit his effectiveness as one of the most powerful immortal anime villains despite his immense magical abilities. He starts to wish for an end to his eternal life, turning his immortality into a curse.

8) Griffith (Berserk)

Griffith as seen in Berserk 2016 (Image via Millepensee, GEMBA)

Griffith, later known as Femto, is one of the most complex and morally ambiguous villains. He is a charismatic and driven leader of the Band of the Hawk who aspires to establish his own kingdom. His transformation into a demonic being grants him immortality and immense power, but it comes at a cost. Griffith is a terrifying opponent because of his ambition and willingness to sacrifice everyone and everything to accomplish his goals.

Following his transformation into Femto, Griffith joins the God Hand, an organization of strong demonic creatures who can control fate and channel dark energies. He gains powers in his new form far beyond those of a typical human, such as controlling time and reality.

Griffith's strategic mind and ruthless ambition make him capable of orchestrating complex schemes and manipulating others to achieve his goals, making him one of the most terrifying immortal anime villains.

7) Muzan Kibutsuji (Demon Slayer)

Muzan as seen in the anime (Image via Studio Ufotable)

The father of all demons in Demon Slayer, Muzan Kibutsuji, is a mighty and devious enemy. As the first demon, Muzan possesses incredible regenerative abilities, shape-shifting, and immense strength. He can turn people into demons with his blood, and his army of devoted followers serve him without question. Muzan's cunning and adaptability make him a persistent threat to humanity.

Muzan's immortality and regenerative abilities make him nearly invincible in battle. With his shape-shifting abilities, he can disguise himself to fit in with human society and heal from nearly any injury. Muzan is a master manipulator thanks to his intelligent and cunning mind making him one of the most fearful immortal anime villains. His inability to walk in the sun is Muzan's ultimate weakness.

6) Zamasu (Dragon Ball Super)

Zamasu as seen in Dragon Ball Super (Image via Toei Animation)

One of Dragon Ball Super's most formidable and dangerous immortal anime villains is Zamasu, a former Kai who turned evil. His quest for immortality through the Super Dragon Balls stemmed from his obsession with justice and his conviction that gods are superior to mortals.

After achieving his goal, Zamasu's fusion with Goku Black creates Fused Zamasu, a being of God-like power and immortality. Fused Zamasu possesses immense strength, speed, and durability, and the ability to manipulate energy and create powerful attacks.

Because of his immortality, he is nearly unbeatable because he can heal from any wound and fight without getting worn out. Zamasu is one of the strongest immortal anime villains who can take on multiple formidable opponents at once thanks to his divine abilities and fusion with Goku Black.

5) Dio Brando (JoJo's Bizarre Adventure)

Dio as seen in the anime (Image via David Production)

Dio Brando, the iconic vampire from JoJo's Bizarre Adventure, is one of the most memorable and powerful immortal anime villains. Dio obtains The World, the Stand, which has the ability to halt time, after becoming immortal through a stone mask. His formidable strength, brutality, and cunning make him a legendary antagonist who has a long-lasting effect on the series.

Dio has superhuman strength, speed, and regenerative abilities thanks to his immortality and vampire abilities. He can pause time for a brief period using his Stand, The World, which offers him a considerable tactical advantage. Because of his cunning and strategic thinking, Dio earns his place among the list of strongest immortal anime villains.

4) Father (Fullmetal Alchemist: Brotherhood)

Father [Homunculus] as depicted in the anime (Image via Studio Bones)

Father, the primary antagonist of Fullmetal Alchemist: Brotherhood, is a homunculus who seeks to become a god. He is one of the strongest immortal anime villains due to his massive alchemical manipulation skills, soul-absorbing abilities, and ability to heal from any wound.

Father's origins as a being created from the essence of a powerful alchemist give him a deep understanding of alchemical principles, which he employs to devastating effect. Father's abilities include creating and commanding other homunculi, each with unique abilities.

He can also manipulate the very fabric of reality, using alchemy to reshape the world around him. His ultimate objective is to become an all-powerful being with the ability to rule the entire universe by absorbing the power of God. His knowledge and skills combined with his thirst for power make him one of the most powerful immortal anime villains.

3) Aizen (Bleach)

Aizen after merging with the Hogyoku (Image via Studio Pierrot)

One of the strongest and most devious immortal anime villains is Sōsuke Aizen, the former captain of the 5th Division in Bleach. Aizen gains immense spiritual power and immortality after fusing with the Hōgyoku. He is almost unbeatable as a foe because of his mastery of Kido, combat, and the use of Kyoka Suigetsu, his Zanpakuto, to manipulate others.

Aizen is a strong opponent in combat because of his immortality and strong spiritual pressure. He can create perfect illusions with the help of his Zanpakuto, Kyoka Suigetsu, which distorts his opponents' perceptions and makes Aizen unpredictable. With this great advantage of being able to manipulate others, Aizen can easily outmaneuver and outsmart his opponents.

2) Kaguya Ōtsutsuki (Naruto)

Kaguya as seen in the anime (Image via Studio Pierrot)

Kaguya Ōtsutsuki, the progenitor of chakra in the Naruto universe, is a being of god-like power and immortality. She has enormous chakra reserves and dimension manipulation skills. She is an almost unbeatable opponent because of her superior strength and skill set compared to all other characters in the series.

Among Kaguya's abilities are the capacity to control and create dimensions, alter reality, and launch potent chakra-based attacks. She can cast strong genjutsu and have unmatched perception thanks to her Byakugan and Rinne Sharingan. As one of the strongest immortal anime villains and her capacity for regeneration, Kaguya is difficult to overcome in a straight fight.

1) Yhwach (Bleach)

Yhwach as seen in Bleach: TYBW (Image via Studio Pierrot)

Yhwach, the Father of all Quincy and the main antagonist of Bleach's Thousand-Year Blood War arc, is ranked top amongst the most powerful immortal villains. He is an extremely dangerous foe due to his near-omnipotence, capacity to absorb and disperse souls, and ability to control the future. Yhwach's special talent, The Almighty, gives him the ability to predict and change the course of events, making him almost unstoppable as an enemy.

Yhwach gains strength and influence throughout the Thousand-Year Blood War arc by taking on the abilities of strong beings and using them to his advantage. It will take the combined efforts of several strong characters who can exploit a weakness in his abilities to defeat him. Yhwach's immense power, immortality, and ability to manipulate the future make him the strongest of the immortal anime villains.

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Edited by Ivanna Lalsangzuali