Houston vs Cincinnati prediction & betting tips - September 21 | College Football Week 4

Houston (1-2) vs. Cincinnati (2-1), which takes place on Saturday in Week 4, is a rivalry game between two teams that have faced each other many times over the years. This game will be the 30th time the two teams have faced, dating back to 1957.

The Cougars will try to continue its positive momentum after beating Rice 33-7 last week. This comes after Houston lost to UNLV 27-7 in week 1 and then lost to No. 15 Oklahoma 16-12 in Week 2.

The Bearcats started off the season with a 38-20 win over Towson. However, they lost a close 28-27 matchup against Pittsburgh in Week 2. They bounced back with a 27-16 win over the Miami Redhawks in week 3.

Houston vs Cincinnati prediction

The odds project that the Houston vs Cincinnati matchup should be a close one. Cincinnati is a slight favorite but only at -165 odds. So, the oddsmakers think this game could go either way, with a slight edge given to the Bearcats.

Despite only winning one of its first three games, the Cougars have some positive things to take from its first three games. Notably, the team's defense has done a good job of limiting points.

The most points Houston has given up in a game is 27 and limited its opponent to less than 20 in two of its games. However, the offense has struggled, failing to put up more than 16 points in either of its first two games.

Cincinnati is the opposite, having no trouble generating offense. The Bearcats have put up at least 27 points in all three games. However, it has allowed 20 or more in two games and 16 in the other. The Bearcats will need to tighten things up defensively to get a win on Saturday.

While the odds are close, we give the edge to Cincinnati. The Bearcats have proven they can put up points even in losing efforts. They have won twice, and their only loss was by one point. So, we're picking Cincinnati to win.

Houston vs Cincinnati betting tips

Tip #1: Bet on Cincinnati's side of the spread, -3.5 (-109).

Tip #2: Bet the over, 47.5 points (-110).

Tip #3: Bet on whichever side of the money line you prefer. There are good odds for both teams, the Bearcats (-165) and Cougars (+140).

Houston vs Cincinnati head-to-head

This will be the 30th matchup between these two teams, and Houston has the edge with a 15-14 record. However, lately, the matchup has favored Cincinnati. The Bearcats have an 8-2 record in the last 10 games, which includes a 24-14 win last year.

How to watch Houston vs Cincinnati

The game will be broadcast on Fox Sports 1. Fans can also stream the game on Fubo TV.