Minnesota vs. Michigan prediction and betting tips - September 28 | College Football Week 5

The Minnesota Golden Gophers travel to Ann Arbor to take on the No. 12 Michigan Wolverines in a Week 5 Big Ten matchup.

The Gophers are 2-2 after their Week 4 loss to Iowa. Minnesota looked modest to begin its season, opening with a 19-17 setback versus UNC before rattling off back-to-back wins ahead of the team's Week 4 defeat.

Conversely, Michigan has found new life after its Week 4 win over No. 11 USC. With Alex Orji leading the way, the Wolverines appeared to find their offensive identity, rattling off 290 rushing yards against Southern Cal. Many counted out Michigan following its Week 2 blowout loss to Texas, but the Wolverines have responded well.

With these Big Ten foes set to meet this weekend, here is an official game prediction and betting tips for the contest.

Minnesota vs. Michigan: Prediction

This pick is relatively cut and dry. The Wolverines have one of the best rushing attacks in the country. The Gophers struggled mightily against the run in their two losses, allowing 147 rushing yards versus North Carolina and 272 rushing yards versus Iowa.

We're taking the Wolverines in this matchup, but the Gophers could manage to keep it close. Michigan has struggled this season against lesser opponents.

Minnesota vs. Michigan: Betting Tips

Tip 1: Michigan Wolverines -10 (-105)

Tip 2: Total Points Over 35.5 (-115)

Tip 3: Kalel Mullings Longest Rush Over 20.5 Yards (-122)

Minnesota vs. Michigan: Head-to-Head

On Saturday, Michigan and Minnesota will play the 96th installment of their rivalry, which dates to 1920. The Wolverines have dominated the series and lead the Gophers 77-21-2.

Michigan has won nine of the series' last ten matchups, including a four-game winning streak against Minnesota. The Wolverines' largest margin of victory came in 2011 when they topped the Gophers 58-0. Minnesota's last win came in 2014 when it defeated Michigan 30-14.