Northwestern vs. Purdue prediction and betting tips - November 2 | College Football Week 10

The Purdue Boilermakers will host the Northwestern Wildcats at Ross-Ade Stadium for a Week 10 Big Ten Conference matchup. The game is scheduled for Saturday at noon ET. Purdue (1-6, 0-5 Big Ten Conference) has lost six straight after their season-opening win against Indiana State and is coming off a 35-0 loss to the Oregon Ducks before last week's open week.

Northwestern (3-5, 1-4) is looking to snap its two-game skid, coming off a 40-14 loss at the hands of the Iowa Hawkeyes last Saturday. After a 2-1 start to the season, Northwestern has just won one of its last five games.

While this matchup won't have playoff implications, Northwestern is looking to become bowl-eligible with four games left on their schedule. Here are our predictions for this matchup, including three betting tips.

Northwestern vs. Purdue: Prediction

This game is a tough one to predict for several reasons. First, both Purdue and Northwestern are at the bottom of the Big Ten standings. Secondly, both schools feature the two lowest-scoring offensive units in conference play. Considering these factors, we'll take the home team this weekend.

The week before they were shut out by Oregon, the Boilermakers' offense took Illinois the distance, suffering a 50-49 loss. Purdue's high-powered rushing attack, led by Devin Mockobee, should lead them to a win over Northwestern.

Northwestern vs. Purdue: Betting Tips

Tip 1: Purdue Boilermakers +1 (-110)

Tip 2: Purdue Total Points Over 22.5 (-125)

Tip 3: Northwestern Total Points Under 23.5 (-115)

Northwestern vs. Purdue: Head-to-Head

Purdue has been dominant in this rivalry's 128-year history. This weekend will mark the 89th meeting between the Boilermakers and Wildcats. Purdue has won 53 of 88 matchups, while the Wildcats have 34 wins, along with a 7-7 tie in 1932.

The Boilermakers have struggled throughout the series' last 10 matchups as Northwestern has won seven games. Purdue will look to avenge their 23-15 loss to Northwestern last season in Evanston.