Ole Miss vs. LSU: Score prediction for College Football Week 7 ft. odds & picks

The No. 9 Ole Miss Rebels will travel to Baton Rouge this weekend to take on the No. 13 LSU Tigers in a highly anticipated Week 7 showdown. The Southeastern Conference clash will likely have playoff implications as both teams have one loss each.

The Rebels are on the back of a 27-3 win over the South Carolina Gamecocks in Week 6, moving up three spots in this week's AP Top 25. The Tigers, on the other hand, did not play in Week 6, but notched a win their last time out, topping South Alabama in a dominant 42-10 win.

Ole Miss enters the game on Saturday as the favorite to win, but LSU could pull off an upset at home.

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Ole Miss vs. LSU score prediction Week 7

This game's over/under is set at 63.5 total points, per ESPNBet. Sportsbooks and experts expect this to be a high-scoring matchup between familiar SEC foes.

The Rebels' offense has struggled over the last two weeks versus two SEC opponents, scoring a combined 44 points. LSU's offense posted 36 points versus South Carolina in Week 3, but only notched 20 points versus the No. 23 USC Trojans two weeks prior.

Taking the game's point spread and over/under into account, we'll take Ole Miss over LSU 31-27.

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Ole Miss vs. LSU point spread prediction

The point spread for this Week 7 clash is currently set at 3.5 points, meaning Ole Miss would have to win by four or more points to cover. LSU could cover with a win or lose by a field goal or less.

Looking back at LSU's matchups versus South Carolina and USC, the Tigers failed to cover the spread in each of these games. Using these matchups as indicators of this week, as both teams are the strongest opponents the Tigers have seen thus far, picking Ole Miss to cover the spread and win by four or more points would be the right call.

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What time is the Ole Miss vs. LSU game on?

Ole Miss vs. LSU is scheduled for a 7:30 pm ET kick off on Saturday. Coverage for the game will be available on ABC and ESPN+.