Ole Miss vs. South Carolina: SI score prediction for College Football Week 6 ft. odds & picks

Images via Instagram accounts of both teams — Ole Miss vs. South Carolina score prediction for college football Week 6 (image credits: instagram/olemissfb, gamecockfb)

The Ole Miss Rebels (4-1) will face the South Carolina Gamecocks (3-1) on Saturday at 3:30 p.m. ET. This Week 6 matchup will be a big test for the Gamecocks as the team will look to start strong after an open week.

The Rebels enter the game as the No. 12-ranked team in the nation. They are coming off their first loss of the season against Kentucky (20-17). The offense struggled in the game and the Rebels ultimately lost to an unranked opponent.

Ole Miss vs. South Carolina score prediction Week 6

These two teams head into the matchup with strong records with only one loss each. The Rebels are a strong favorite due to their ranking; however, it should not be an easy matchup for them.

South Carolina has done a good job of generating offense this season and has been getting progressively better. The team started the season with a 23-19 win over Old Dominion and followed it up with a 31-6 win over Kentucky.

The Gamecocks then suffered their only defeat of the season to No. 13-ranked LSU (36-33). While it was a loss, it was a close one to a ranked opponent. In Week 4, they bounced back with a 50-7 victory over Akron.

Ole Miss got out of the gate hot this season, winning its first four games. The wins were: 76-0 over Furman, 52-3 over Middle Tennessee, 40-6 over Wake Forest and 52-13 over Georgia Southern.

Based on these trends, we are predicting a close win for Ole Miss. We project a score of 31-24. The biggest indicator that the game will be close is both teams have faced Kentucky. Despite being a stronger team on paper, Ole Miss lost to Kentucky while South Carolina beat them.

Ole Miss vs. South Carolina point spread prediction

FanDuel has Ole Miss as a nine-point favorite. As a result, based on our score prediction and the spread, we predict that South Carolina will cover it in a losing effort.

Ole Miss vs. South Carolina computer prediction

SI had its analytics model project for this game and in 20,000 simulations, it had Ole Miss winning 75.4% of the time. It uses the Football Power Index computer prediction model.