Virginia Tech vs. Syracuse prediction and betting tips - November 2 | College Football Week 10

The Syracuse Orange will host the Virginia Tech Hokies at JMA Wireless Dome on Saturday for a Week 10 Atlantic Coast Conference matchup. The Orange will look to bounce back after a 41-13 blowout loss to the Pitt Panthers with a season-high five turnovers from their offensive unit. Syracuse enters Week 10 with a 5-2 record, with a 2-2 record in the ACC standings.

After a 2-3 start for the Hokies, Virginia Tech has bounced back, managing three straight wins to bring their record to 5-3 entering the weekend with a solid 3-1 record in conference play. The Hokies are coming off a 21-6 win over Georgia Tech in Week 9, with three consecutive wins versus ACC opponents.

Here are predictions and betting tips for this Week 10 ACC matchup.

Virginia Tech vs. Syracuse: Prediction

This is a tough matchup to predict. Both teams feature explosive offensive units but have struggled defensively throughout the season. While Virginia Tech enters the week as a 3.5-point favorite over Syracuse, the Orange have posted a 3-1 record at home this season, suffering a two-point loss in their lone slip-up.

This is set to be one of the highest-scoring games of the Week 10 slate and with that in mind, we'll take the home team in Syracuse. The Orange have shown the ability to win the close games, boasting a 3-1 record in games decided by one possession, while Virginia Tech is 0-3.

Virginia Tech vs. Syracuse: Betting Tips

Tip 1: Syracuse Orange +3.5 (-110)

Tip 2: Total Points Over 54.5 (-105)

Tip 3: Kyle McCord Two or More Passing TD (-225)

Virginia Tech vs. Syracuse: Head-to-Head

The Virginia Tech-Syracuse rivalry is relatively new. Dating back to 1964, the Hokies and Orange have squared off 20 times. Syracuse has claimed 11 wins, with Virginia Tech winning nine games in the series.

In last year's matchup, the Hokies walked away with a 38-10 win in Blacksburg, avenging their two-game skid after two losses in 2020 and 2021. Kickoff for this ACC showdown is scheduled for noon ET on Saturday, with coverage available on the CW Network.