#2 Atletico's injury woes
Diego Simeone has built his team around a strong defense since his arrival, but he has had to deal with a lot of injured players lately, especially in defensive positions. Godin and Gimenez who are the foundation of Atletico's rock solid defense are injured, and Juanfran is also doubtful as he is suffering from a calf injury.
Simeone will be helpless without his defensive powerhouses against the formidable Barcelona attack. The likes of Messi, Suarez, Coutinho, and Dembele will look to threaten the home side with their pace and agility. The lack of experience on the pitch might come back to haunt Los Colchoneros.
Koke and Lemar were also sidelined due to muscle and thigh injuries, and Simeone will definitely need such playmakers to break through in counter attack. All in all, it will be a test of character, mental strength, and temperament for Simeone's men against the reigning champions.