#3 The Harry Kane conundrum
Harry Kane's meteoric rise in the Premier League has coincided with Tottenham Hotspurs' resurgence as title contenders in the last two seasons or so. He is one of the instrumental reasons for his side's incredible results in recent years and has also claimed the coveted Golden Boot in each of the last two seasons.
So there is no denying Kane's influence on this team and his absence from the trip to Fulham Road is nothing short of a psychological blow to Spurs.
Having accounted for almost 41% of the league goals so far this term, the stats show how much they thrive in his scoring prowess and without him, Pochettino would be devoid of a genuine No.9.
Son Heung-min is most likely to fill in his boots, but the Korean, for all his rich vein of form, hasn't enjoyed much success in that role nor brings the same level of verve that Kane does, going forward.
Even if the attacking triumvirate of Son, Christian Eriksen and Dele Alli look fearsome enough, the absence of Kane comes with its own bearings and it might hurt them a bit.