#1 Attack often through the left flank
As Aaron Ramsey started last weekend against Chelsea, it might either be Mesut Ozil or Alex Iwobi taking on the playmaking duties. If it will be Ozil, Emery will probably stick to a 4-4-2 diamond, but with Iwobi, he would switch back to a 4-2-3-1, as Iwobi's chemistry with Kolasinac has often paid off on the pitch.
Ashley Young is likely to play on the right flank for Manchester United, and the Englishman loves to drive forward, leaving huge gaps behind him for the opposition to counter-attack. Though Victor Lindelof has been doing pretty well under Ole, it will be a tough task for him to keep Pierre-Emerick Aubameyang silent, due to his extraordinary positioning and pace.
Kolasinac should be allowed to attack freely through the left, as his attacking abilities can come handy for the Gunners. It would be better if Emery stuck to his 4-4-2 diamond formation, as it offers incredible stability and balance in all positions on the field.
A win for Arsenal will ensure their qualification, and it will be a big boost for the London side, whereas Manchester United will experience their first defeat under their new gaffer. However, a win for United would cause serious trouble for Arsenal, regarding confidence and form.