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#4 Chile vs Brazil
Brazil are the only team from the CONMEBOL leg of qualifiers to have secured a place in the World Cup and wouldn't be hesitant to deny Chile a place in the global event.
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Chile have a goal difference of +2 while the Argentines trail close behind with a goal difference of +1. Argentina would be eagerly hoping for Brazil to defeat Chile, which could possibly improve Argentina's chances to qualify directly for the World Cup.
Having tasted bitter defeat at the hands of the Chile national team in two consecutive Copa America finals, Argentina will get indirect revenge if Chile lose to Brazil.
Chile are third in the table with 26 points, one point more than the Argentines and play away against Brazil, which is arguably the strongest team in South America at the moment.
With Chile having problems of their own, the result of the game could be eventful in the points standings, where six teams are still in contention for direct qualification spots and the playoff spots for the 2018 FIFA World Cup.
