#3 The brace that knocked Real Madrid out of the Champions League - 27 April, 2011
Real Madrid and Barcelona were paired in the semifinal of the 2010-11 Champions League and this meant that the eternal rivals would meet each other four times in the space of 20 days, with La Liga and Copa del Rey fixtures completing the quartet.
A Cristiano Ronaldo header decided the Copa final and with the league all but certain to end at Camp Nou, the Champions League fixture took on extra significance.
Both sides lined up at the Santiago Bernabeu just a week after the Copa del Rey final and in what was one of the most heated affairs in this storied rivalry, the two teams threw caution to the wind, with tackles flying recklessly and multiple cards issued.
Messi received the brunt of the Madrid aggression, with a double-team of Lassana Diarra and Xabi Alonso shadowing his every move and a particular run of play where five Madrid players surrounded the Barcelona number 10 as he drove forward is one of the defining images of the Champions League.
That did not, however, deter the Argentine and he ended the night with a brace to send Barcelona through to the final against Manchester United at Wembley.