#2 Isco
Isco is easily one of La Furia Roja's most talented footballer and a lot could ride on his performance at the World Cup. Having established himself as a key member of the side at Real Madrid, Isco will be determined to do his best for his national side this month.
Like Ramos, Isco too is entering the World Cup on the back of a third consecutive UEFA Champions League title and will be high on confidence. This past season, the attacking midfielder scored 8 goals and assisted 9 more.
His creativity in midfield will be a crucial factor if Spain are to succeed, and such is the significance of the 26-year-old, that many have touted him to win the Golden Ball at the end of the tournament.
On the international stage, Isco has only made 26 appearances for Spain but has scored 10 goals in those matches. Devoid of a permanent spot as a result of Zidane's rotational policy so far, Isco will hope to make the World Cup his own and take his game to the next level.