Record 35-time Serie A champions Juventus continued their march towards a record-extending ninth consecutive league title by beating Fiorentina 3-0 at home in a matchday 22 fixture of the 2019-20 season.
The win helped the Bianconeri open up a six-point lead atop the league standings before second-placed Inter Milan's 2-0 away win at Udinese reduced the champions' lead to three points.
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AC Milan's five-match winning run in all competitions ended following a 1-1 home draw with Sampdoria. Elsewhere, third-placed Lazio were back to winning ways with a convincing 5-1 home win over SPAL after their 11-game winning run in the league was ended by fierce cross-town rivals AS Roma.
Champions League debutants Atalanta, whose 59 goals are the most scored by any team in the Italian top-flight this season, remain in fourth place following a 2-2 home draw against Genoa.
On that note, let us have a look at the five talking points from the 22nd matchday of the 2019-20 Serie A season:
#1 Cristiano Ronaldo quickest to score 50 Juventus goals
Making his 70th appearance in all competitions for Juventus, Cristiano Ronaldo scored a pair of penalties against Fiorentina in the Bianconeri's 3-0 home win on matchday 22 of the ongoing 2019-20 Serie A season.
In the process, the 34-year-old Portuguese player became the quickest to reach the milestone of scoring 50 goals for Juventus - a tally which includes 40 goals in Serie A, eight in the UEFA Champions League, one in the Coppa Italia, and one in the Super Coppa Italiana.
It marked the ninth consecutive Serie A game Ronaldo scored in, emulating French striker David Trezeguet, who also did so for the Bianconeri in 2005.
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#2 Juventus become the first team to register 1600 Serie A wins
Eight-time defending champions Juventus notched a league-leading 17th win of the ongoing 2019-20 season following a comfortable 3-0 victory at home to visiting Fiorentina on matchday 22.
In the process, the record 35-time Serie A champions became the first team to register 1600 wins in the Italian top-flight.
#3 Ciro Immobile ties 61-year old Serie A record for most goals in a season after 21 games
Continuing his prolific goalscoring run in the Italian top-flight this season, Ciro Immobile's brace helped Lazio to a 5-1 home win over SPAL as the capital club returned to winning ways after seeing their club-record 11-game winning run come to an end in a 1-1 draw away to AS Roma last month.
In the process, the Italian striker notched up his 25th goal of the campaign in just 21 games, tying a 61-year-old record of Antonio Valentin Angelillo for most goals at this stage of a Serie A season.
Following the brace, Immobile leads Cristiano Ronaldo by six goals atop the 2019-20 Serie A goalscoring scoring chart.
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#4 Romelu Lukaku is the first player to score 11 or more goals in his first 11 Serie A away games
Continuing his fine form in his debut season in Italy, Romelu Lukaku's brace at Udinese on matchday 22 helped Inter Milan stay within three points of league leaders and defending champions Juventus.
In the process, the Belgian striker became the first player to score 11 plus goals in his first 11 Serie A away games.
Lukaku's 16 goals from 22 games this season is only bettered by Immobile (25) and Cristiano Ronaldo (19).
#5 Edin Dzeko becomes the seventh player to score 100 goals for AS Roma in all competitions
Playing his 159th Serie A game in his fifth season with AS Roma, Bosnian striker Edin Dzeko's second half penalty against Sassuolo on matchday 22 made the 33-year-old the seventh player to score 100 goals in all competitions for the capital club.
Dzeko's tally of 100 consists of 72 goals in Serie A, two in Coppa Italia, and 26 in European competitions.
Dzeko's tally of 100 consists of 72 goals in Serie A, two in Coppa Italia, and 26 in European competitions.