#4 Taking advantage of Pogba and Fellaini's absence
Manchester United's good performances this season have to be attributed to the solidity their midfielders have provided. While Matic has done a phenomenal job at shielding the back four and distributing possession, Paul Pogba has been involved in creating chances for the attackers and also finding the back of the net himself on occasion.
However, due to a hamstring injury, he will play no part in the weekend game against Liverpool. Another player set to miss out will be Pogba's replacement - Marouane Fellaini. The Belgian midfielder has gone on from being a scapegoat to a saviour for Mourinho's side in the absence of Pogba, but injury has ruled him out of the game as well.
This will see Mourinho turning to Ander Herrera - a player that has started in a solitary league game this season. The 28-year-old isn't used to playing alongside Matic, and their lack of chemistry in the middle of the park could see Klopp's men take advantage of it.
Emre Can could be given the job to man mark the Spaniard in a similar way Herrera dealt with Eden Hazard in United's 2-0 win over Chelsea last season. Herrera is expected to be the Red Devils' ball carrier, and stopping him could nullify United's threat from the middle.