#4 Real Madrid 0-3 Barcelona, 2017

This Clasico was vital for Real's title hopes last season. A win for Barcelona would have sent the Catalans 14 points clear, effectively ending any title race. And that is what happened.
Zidane sacrificed Isco's creativity and started Mateo Kovacic alongside Casemiro to control the midfield. Kovacic was particularly tasked to smother Lionel Messi.
This plan backfired as Barcelona won 3-0 quite comfortably. Ivan Rakitic ambled through the Real midfield with no one to stop him as Messi cleverly diverted Kovacic away. The move led to the first goal and Barca did not look back. Another counter-attack saw Dani Carvajal handle in the box. Penalty, red card, game over.
This game effectively was Real's surrender of their title and Zidane failed to do anything on the day to stop it.