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#5. Sadio Mane
In a major setback to Liverpool's wonderful start to the season, it was confirmed that Mane fractured his left thumb during Senegal's 3-0 win over Sudan on Saturday.
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The speedy winger didn't feature in the return fixture and was immediately assessed by Liverpool's medical staff.
In an official post, Liverpool later confirmed that the Senegalese successfully underwent a surgery on 17 October and his recovery is closely monitored.
Fortunately for the Reds injury concerns over Van Dijk and Salah were quashed as the duo took part in full training before their clash with Huddersfield.
#6. Nemanja Matic
The former Chelsea midfielder Nemanja Matic withdrew from Serbia's squad for the UEFA Nations League last week, due to a back injury.
He has been undergoing treatment at United's training base ever since. But, according to reports, he may not be able to recover in time for the showdown between Manchester United and Chelsea.
Sky Sports News also reported that he remains a major doubt for the trip to face his former club Chelsea at the Stamford Bridge.
