Centre midfield : Victor Wanyama
The Kenyan might become Spurs' best bit of business in recent times as the former Southampton man has settled in well with his new squad and has brought a solid presence in Spurs' midfield. With Dembele out injured, Wanyama's importance has increased in the team and gets his place in this lineup ahead of the likes of Mohammed Elneny and Granit Xhaka as the duo might not be fully prepared to play in the hotly contested Derby.
Centre midfield : Santi Cazorla
The Spaniard has rediscovered himself in a deeper role as Cazorla has started to influence on games more than he did before as he is dictating the Gunners' play from midfield. With Wanyama in this lineup, Cazorla can have the freedom to move forward and can spray passes all over the field. Aaron Ramsey has just returned from an injury and the likes of Moussa Sissoko and Eric Dier have not played to their full potential yet.
Attacking midfield : Mesut Ozil
Alli is improving with each passing game but the German is on an altogether different level in the no.10 role. Along with his defence-splitting passes, Ozil has added goals to his game this campaign. His finish against Ludogorets in the midweek was plain stunning. He is one of the best in the world in his position and is another must-have player in any combined eleven.