The two most successful teams in the FA Cup history are set to take on each other at Emirates in a highly anticipated fourth-round fixture.
Manchester United are on an impressive run with 7 wins in 7 matches under Ole Gunnar Solskjaer while Unai Emery's Arsenal are high on confidence after beating London rivals Chelsea at home in the weekend.
The last encounter between the sides ended in a 2-2 draw at Old Trafford in December with the Red Devils coming back twice after going a goal down
Team News
Arsenal
The Gunners were dealt with a huge blow when full-back Hector Bellerin was stretchered off in their last match with a ruptured ligament. The Spaniard joins Rob Holding, former United striker Danny Welbeck on the injury list. Another former Red Devil Henrikh Mkhitaryan has returned to training and may feature against his former club.
Mesut Ozil is fit and available but his participation in the tie will depend upon his manager's discretion.
Manchester United
Ole Gunnar Solskjaer has confirmed that defenders Chris Smalling and Marcos Rojo have returned to training but will be unavailable. Luke Shaw is a doubt for the fixture after the left-back was pulled out of the starting XI just before the kickoff against Brighton due to illness. However, he has travelled with the squad and could be a surprise inclusion in the playing XI.
Marouane Fellaini is another casualty on the United injury list with the Belgian expected to be back only after a couple of weeks.
The Norwegian has confirmed that Alexis Sanchez will feature against his former club for the first time at the Emirates after leaving the Gunners last season.
Spanish goalkeeper David de Gea is the only major exclusion from the travelling squad with United Number 1 missing in the travelling squad.
Probable Lineup
Arsenal(4-3-1-2): Leno; Maitland-Niles, Sokratis, Koscielny, Kolasinac; Torreira, Guendouzi, Xhaka; Ramsey; Lacazette, Aubameyang
Manchester United(4-3-3): Romero; Young, Smalling, Lindelof, Dalot; Fred, Pogba, Herrera; Sanchez, Lukaku, Lingard