Defence:
The back four is going to have to do with some changes since one of Ole's starter will miss this tie with a suspension. With that in mind, Ole is going to have to make some decisions on who to start in that left back role.
The obvious starter is going to be Ashley Young in the right fullback position and on the other side, the manager is going to have to decide between Diogo Dalot, Marcos Rojo and Matteo Darmian. It is likely that the manager will go for the Argentine Marcos Rojo in this tie since he's, first of all, left-footed and has far more experience playing there.
The two centre back positions are going to be occupied by Chris Smalling and Victor Lindelof. Chris Smalling and Victor Lindelof have developed a good understanding that Ole will want them to continue playing together as many games as possible.
Ashley Young, Chris Smalling, Victor Lindelof, Marcos Rojo.