Midfield: Paul Pogba, Scott McTominay and Fred
Paul Pogba had to play a much defensive role against Liverpool, which he did to perfection. Against Crystal Palace, he might be the most experienced in the midfield without Nemanja Matic and Ander Herrea, so he might have to take up more responsibility.
Scott McTominay was absolutely fantastic against Liverpool. He has many similar traits to the still unavailable Nemanja Matic. McTominay may start his second consecutive game on Wednesday and will be looking to keep up his good work.
With injuries to Ander Herrera and Nemanja Matic, Fred may finally get his opportunity to impress Solskjaer in the Premier League. The Brazilian hasn't really featured since his appearance against Reading in the FA Cup and he may get his chance on Wednesday.