Right-back: Trent Alexander-Arnold
What a change a player could undergo in a span of few months! The Reds youngster was merely a fringe player last year.
But this term, he's giving the likes of Manchester City a good run for their money. It has been a fine return to fettle after a lengthy lay-off with injuries at the start, and he's sure to feature again in the line-up against Roma.
At only 19, he has the confidence and the temperament that belies his age and as witnessed in the quarter-finals, can cause troubles to even the best of teams with his darting runs.
One of Roma's weakest links is the left-back, and Arnold could more than exploit it to their advantage.
Centre-back: Kostas Manolas
The man who sounded Barcelona's death knell with a late strike, Manolas has grown into such a key figure at the heart of the Roman backline.
Rough and rugged, his dominance on the ball stretches aerially too, where he's enjoyed 74% success rate this season in Serie A.
The Greek defender times his tackles to perfection and unrelenting when it comes to man-marking.
Just ask Lionel Messi. He's a big threat from the set-pieces too, and Roma would be looking up to him whenever they need a score from one.
Centre-back: Virgil Van Dijk
He may have joined only in January, but the Dutch sensation has already become an anchorman at the back.
Van Dijk has acclimatised to Liverpool's set-up like a fish to water and his recent performances show why Liverpool pursued him for so long.
The 26-year old's 89% pass accuracy is unmatched by anyone in the team. His tall, statuesque stature also given the aerial advantage.
Van Dijk is an excellent reader of the ball, and with 89% passing accuracy, he's the key to building from the back.
Left-back: Andrew Robertson
Roped in as merely a back-up to the injured Alberto Moreno, the 24-year old has made the left-back spot his own. He has impressed the Kop so much, he's deemed as their very own Maldini!
Robertson is a revelation down that flank, bombing forward with panache and laying off lethal crosses into the box with which he's assisted four times this season.
He brings defensive stability whilst also a great distributor of the ball with 87% passing accuracy.
Liverpool's left-back slot was a thing of mystery for many years. But in Robertson, they may have found the panacea to all their problems in that position.