#1 David De Gea
David De Gea has unarguably been Manchester United's best player in the past few seasons.
Where Mourinho's men failed to deliver on various occasions, the Spaniard has made his mark by standing tall between the poles.
United has failed to establish a strong defence since Sir Alex Ferguson left the club in 2013 but De Gea has been like a wall, often bailing them out with crucial points.
In my opinion, it will be a mammoth task to contain the attack of Manchester City, who have been scoring goals for fun lately.
The home side will be brimming with confidence having scored six in each of their last two home games against Southampton and Shakhtar Donetsk.
City will look to create chances and trouble the United defence with their passing and movement with the ball.
In order to stay in the game, De Gea will have to make some important saves to give his side the opportunity to counter-attack in Mourinho's style.
His consistent performance would be inevitable for the visitors who have never lost at the Etihad under Mourinho's tenure.
Stopping the likes of Aguero, Sterling, Sane, David Silva and Bernado Silva will not be easy for the defenders and it may require much assistance from De Gea to help his side stay in the game.
We may witness another thrilling encounter between the two teams of Manchester and these three players will be key to United's success.
But we will have to wait and see if the home side bags all the three points or the Red Devils will end their noisy neighbor's unbeaten run.