5: Hull 2-1 Leicester, 2016/17
Leicester shocked the world when they won the Premier League back in 2016, and while nobody expected them to retain their trophy, most fans thought they would comfortably see off freshly promoted Hull on the opening day of their title defence.
While they had lost star midfield N'Golo Kante, they still managed to maintain the services of a lot of their Premier League winning team. In stark contrast, Hull were coming into the game with a paper-thin squad and without a permanent manager.
Adama Diomande smashed in the opening goal for The Tigers on the stroke of half-time, and while Leicester fought back through a penalty early in the second half, Hull completed their shocking victory thanks to a goal from Robert Snodgrass.
Hull would go on to be relegated that season but there are fewer things sweeter than defeating the reigning Premier League champions on the opening day of the season.