Defenders:
Carvajal is expected to be playing on the right side of the defence again. He's got a daunting task of keeping Luis Suarez or Lionel Messi quiet for the entire game. One mistake and that could end up in Barcelona scoring. He has to be on the toes of the opponents attackers throughout the match. With Neymar out, one of the other two from MSN are expected to play in that position with Paco Alcaer in the middle.
Captain. Leader. Legend. Sergio Ramos is all set to lead the team out tonight with Nacho partnering him in the heart of the defence. The Spaniard scored the equaliser in the dying minutes of the previous Clasico and would want to score the winner this time around.
With Varane and Pepe out due to injury, Nacho Fernandez will be starting, just like he did vs. Bayern Munich. The 27-year-old did a good job of keeping Robert Lewandowski at bay in the Champions League match, but with Luis Suarez and Lionel Messi, things aren't going to be that simple.
Marcelo has been a regular at the left side of the defence for Madrid for a long time now and is set for yet another match in that position. He made a brilliant run to assist Cristiano Ronaldo during their 4-2 win over Bayern, and if he does something similar tonight, the Bernabeu crowd will go wild.