Left-winger: Henrikh Mkhitaryan (AS Roma)
Injury concerns largely marred Henrikh Mkhitaryan's first half of the campaign, but he has since bounced back strongly.
In the games post the lockdown, the Armenian ace has been sensational, turning in 'Man-of-the-Match' performances with his intelligent passing, brilliant creativity and spectacular vision.
Striker: Munir El Haddadi (Sevilla)
Luuk De Jong might be Julen Lopetegui's first-choice striker in the La Liga. The Dutch targetman could well feature in the Sevilla lineup ahead of Munir El Haddadi.
But it is Haddadi with his bullish strength and deadly finishing skills who's got the Nervionenses so far. With five goals, the ex-Barcelona star has been in rampant form in Europe and could be a handful against AS Roma.
Striker: Edin Dzeko (AS Roma)
AS Roma's chief attacking threat, Edin Dzeko is coming off the back of a stellar campaign that saw him add another feather to his cap.
The Bosnian's exploits made him the joint fourth-highest scorer in the club's history. He could well guide the Giallorossi to their first-ever European glory and etch his name in the history books, having already scored and assisted thrice goals apiece in the Europa League so far.