Defenders:
Šime Vrsaljko (Croatia/Atletico Madrid), Dejan Lovren (Croatia/Liverpool), Stefan Savić (Montenegro/Atletico Madrid), Branislav Ivanović (Serbia/Zenit Saint Petersburg), Matija Nastasić (Serbia/Schalke), Aleksandar Kolarov (Serbia/Roma) and Sead Kolasinac (Bosnia and Herzegovina/Arsenal)
All but one of the players mentioned above have played for one of the Premier League’s big 6. Šime Vrsaljko is the only one who hasn’t played in the Premier League but he plays for Atletico Madrid and that speaks volumes about him.
Stefan Savic, Matija Nastasic and Aleksandar Kolarov have played for Manchester City and have also won the Premier League. Although all three have moved from the Premier League, they still play for clubs in the UEFA Champions League.
Branislav Ivanovic spent 9 years at Chelsea winning all major domestic trophies including the Champions League. The Serbia captain won 10 trophies overall during his time with the Blues and is considered a club legend.
Dejan Lovren and Sead Kolasinac are still playing in the Premier League for Liverpool and Arsenal respectively.