5 former UFC heavyweight champions Francis Ngannou has defeated

#2. Cain Velasquez

Velasquez suffered a first round KO loss at UFC on ESPN 1

Francis Ngannou was the last opponent in Cain Velasquez's illustrious MMA career. During his UFC run, Velasquez won the heavyweight championship on two separate occasions and successfully defended the belt twice.

Velasquez faced 'The Predator' in early 2019 and the bout may have been the most one-sided entry on this list. Ngannou knocked out the former champion in just 26 seconds as he took another step on his eventual path to gold. Velasquez came off a two-and-a-half-year absence to compete in the bout.

Since then, like Dos Santos, Velsquez has spent his time competing in professional wrestling. He even had a WWE feud with his old rival Brock Lesnar, although he has since parted ways with the company.

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#1. Stipe Miocic

Miocic suffered a second round KO loss at UFC 260

Stipe Miocic is unique to this list in that he does hold a win over 'The Predator'. The two have fought twice in 2018 and 2021 and with the series currently being tied at 1-1. While Stipe got the win the first time around, the rematch saw Ngannou win and his first UFC championship in the process.

The first fight between the pair saw Miocic outlast his opponent to earn a unanimous decision victory after five rounds. The rematch saw a more patient approach from Ngannou pay off when he landed a big knockout blow in the second round to win the belt.

Given that each man holds one victory over the other and they both remain at the top of the division, we may very well get a trilogy fight. In fact, a third fight could easily be the next UFC heavyweight title fight. That fight would give Ngannou an opportunity to add another big win to his already ridiculous resume.