#4 Matt Hughes (c) vs George St. Pierre - UFC 65
GSP idolized Matt Hughes, and took him on for the first time in UFC 50, with the vacant Welterweight Championship on the line. Hughes won the first encounter in the first round by submission, and it took two more years for GSP to earn his way back to a title shot against Hughes.
Two years later at UFC 65, GSP faced Hughes, still the champion. However, this was a very different GSP, and his growth as a fighter was evident. This time, he knocked out Hughes in the second round, winning the Welterweight title for the first time.
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They would meet in a trilogy for the interim Welterweight title over a year later, and GSP won, coming out of the trilogy victorious.
#3 George St. Pierre (c) vs Johny Hendricks - UFC 167
This fight was every bit controversial, but it was also equally epic. The fight was GSP's 9th title defence and went the distance, with the bout being one of the rare occasions where St. Pierre was completely outclassed.
This was what led to major shock when the judges scored a controversial split decision favouring GSP. Fans and everyone else were certain that Johny Hendricks had been robbed. Dana White himself disagreed with the decision, and St. Pierre hung up his boots not long after, returning only in 2017.