#2 Weight Cuts
One of the major problems which put a lot of stress on fighters in the UFC are the weight cuts they must undergo. Unfortunately for them, the fights are not 'come as you are' and they have to fit into the weight class of the division in which they are competing.
The entire process is extremely complicated, and losing weight is not easy at all. As a result, often there are many difficulties associated with it. People have an easier time facing the prospect of losing a large amount of weight in a small time. However, that was exactly what they were forced to do.
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Remaining healthy after such a process and actually entering an Octagon to fight another trained professional is not something to scoff at.
This is something WWE stars don't have to encounter, as some UFC stars even encounter health problems due to such drastic weight cuts.