#3 Travel
One of the biggest things that professional wrestlers of years gone by say about the business is the travel. The long-term issues with their health tend to be from the miles they travel in addition to the actual wrestling, which is something that mixed martial artists don't really have to contend with.
If you need two prime examples, then look at CM Punk and Brock Lesnar.
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In the documentary series leading up to his fight with Mickey Gall, Punk said how much better it was to only have to travel a maximum of two hours a day to train as opposed to the lengthy journeys that were endured on the road in WWE. Then you have Brock Lesnar who openly admitted to hating the travel, with it being one of the big reasons that he left the business.
Back onto the more technical side of things for this next entry.