#4. Sean Brady
Sean Brady's perfect record is moments away from its biggest threat yet as he is due to fight UFC veteran Michael Chiesa later today. Should the No.14-ranked contender get the win, he would be well placed for a big year in 2022.
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Brady's record currently stands at 14-0 and he's gone 4-0 thus far in the UFC. He has a well-rounded style to his game and that is reflected by his record that has three knockouts, four submissions and seven decision wins.
Being in the welterweight division may also work in his favor, as dominant champion Kamaru Usman is expected to beat all-comers. The UFC may be intrigued by an undefeated contender like Brady in the later stages of 2022.
#3. Casey O'Neill
Casey O'Neill is just starting to pop up on UFC fans' radar as she has now finished all of her three opponents in the organization. These wins have taken her record to 8-0 and she is another fighter who seems poised for a big 2022.
O'Neill is also likely to benefit from the fact she competes in the UFC women's flyweight division, which features another very dominant champion in Valentina Shevchenko. A fresh contender for the title could again provide an appealing option.
Furthermore, O'Neill defeated the champion's sister Antonina Shevchenko in her last fight. She also has the chance to pick up another high-profile win when she faces Roxanne Modafferi in the latter's retirement fight.
If O'Neill were to win that fight in February and pick up another win over a top-ranked contender later in the year, perhaps she could challenge for the title towards the end of 2022.