UFC Fight Night: Lemos vs. Andrade is a mixed martial arts event produced by the Ultimate Fighting Championship that will take place on April 23, 2022, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States.
UFC Fight Night: Lemos vs. Andrade Main Card
| Weight Class | Fight |
| Women Strawweight | Amanda Lemos vs. Jéssica Andrade |
| Lightweight | Clay Guida vs. Claudio Puelles |
| Heavyweight | Tanner Boser vs. Alexandr Romanov |
| Women Flyweight | Maycee Barber vs. Montana De La Rosa |
| Flyweight | Su Mudaerji vs. Manel Kape |
| Featherweight | Lando Vannata vs. Charles Jourdain |
UFC Fight Night: Lemos vs. Andrade Preliminary Card
| Weight Class | Fight |
| Welterweight | Louis Cosce vs. Preston Parsons |
| Catchweight | Jordan Wright vs. Marc-AndréBarriault |
| Welterweight | Dwight Grant vs. Sergey Khandozhko |
| Light Heavyweight | Tyson Pedro vs. Ike Villanueva |
| Bantamweight | Qileng Aori vs. Cameron Else |
| Light Heavyweight | Marcin Prachnio vs. Philipe Lins |
| Welterweight | Dean Barry vs. Mike Jackson |
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