#2 Cannonier is used to fighting taller, longer opponents
Cannonier is a former heavyweight and light heavyweight. Not only was he significantly undersized in his previous divisions, he will be significantly undersized against Adesanya as well.
At 6 feet tall and with a 77-inch reach, Cannonier is noticeably shorter than Adesanya, who stands at 6 feet 4 inches in height with an 80-inch reach.
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Due to his experience against taller and longer foes, Cannonier understands how to manage distance because he spent a large portion of his career as an undersized competitor.
Overcoming Adesanya's height and reach will not be as challenging for Cannonier as it has been for the reigning champion's other opponents.
#1 Israel Adesanya has become a more cautious fighter
While Adesanya remains one of the sport's most educated strikers, he has strayed from the flashier style that earned him his 'Stylebender' moniker. Since claiming the UFC middleweight title, Adesanya has become a more cautious and defensively-conscious fighter.
He spends the majority of his bouts low kicking and jabbing at range, rendering him less likely to steamroll Cannonier, and more likely to coast to a less dominant decision win as he no longer seeks finishes with as much intent.
This will also grant Cannonier more opportunities to impose his game without the threat of frequently devastating strikes getting in his way.