Best DFS Bets for Sunday-New Orleans Saints vs. San Francisco 49ers-November 27 | 2022 NFL Regular Season

The New Orleans Saints will travel west to face the surging San Francisco 49ers. The Saints are playing out the string while the 49ers push for an NFC West title.

Today we look at the best DFS plays from this intriguing match-up.

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Best quarterback picks

Cash Games: Jimmy Garoppolo, QB, San Francisco 49ers (DraftKings $5.6K, FanDuel $6.8K)

Jimmy Garoppolo has performed well recently and has the weaponry QBs covet. Don't overthink this one.

Tournaments: Andy Dalton, QB, New Orleans Saints (Draftkings $5.3K, FanDuel $6.7K)

Garbage time points count as well. The Saints should have plenty of opportunity in garbage time. It wouldn't be wild to make Andy Dalton your QB in DFS Tournaments.

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Best running back picks

Cash Games: Christian McCaffrey, RB, San Francisco 49ers (DraftKings $8.8K, FanDuel $9.2K)

When he is playing well, Christian McCaffrey is the most dominant force in the RB position. And Scene.

Tournament: Alvin Kamara, RB, New Orleans Saints (DraftKings $7.3K, FanDuel $7.1K)

Many DFS players will flee from Alvin Kamara in this spot. It is true that the 49ers' have a dominant defensive front and will win up front, but Alvin Kamara can be used effectively in the passing game. Adding a talented player in a poor match-up with poor ownership is a standard way to hit it big and gain leverage against the tournament field.

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Wide receivers and tight ends

Cash Games: Brandon Aiyuk, WR, San Francisco 49ers (DraftKings $6.4K, FanDuel $6.7K)

In my opinion, the most essential receiver to the 49ers' success is Brandon Aiyuk. Many will read this and shake their heads as they will likely nominate Deebo Samuel for this distinction. As talented as Samuel is, the 49ers can manufacture touches to Christian McCaffrey and other weapons in the intermediate area. Brandon Aiyuk can be a dominant force on the perimeter, which is critical to the overall success of the 49ers' offense.

Tournament: Chris Olave, WR, New Orleans Saints (DraftKings $6.6K, FanDuel $7.3K)

DFS players may be reluctant to take a chance on rookie sensation Chris Olave. Yes, the San Francisco 49ers are one of the toughest defenses in the NFL. We also have to consider the game script here. The most likely game script is that the San Francisco 49ers overwhelm a defense-less New Orleans Saints defense, and the Saints are playing from behind, down multiple scores, and have to throw the ball significantly more than they would prefer in the second half.

We know Andy Dalton throws a nice deep ball and connected with Chris Olave last week. Olave is one of the most dominant Air Yards threats, so playing the Saints' sensation in your Tournaments is a savvy move.

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