Best NFL DFS Picks for Sunday: Colts vs. Cowboys - December 4 | 2022 NFL Regular Season

The Indianapolis Colts travel to face the Dallas Cowboys in a match-up of two teams traveling in opposite directions.

The Dallas Cowboys appear poised to make a run in the playoffs. Meanwhile, the Indianapolis Colts question the direction of their franchise.

Best quarterback picks

Cash Games: Dak Prescott, QB, Dallas Cowboys (DraftKings $, FanDuel $16K)

The Cowboys should have no problem piling on the points in this one. Dak Prescott will be one of the primary beneficiaries.

Tournaments: Matt Ryan, QB, Indianapolis Colts (Draftkings $, FanDuel $14.5K)

Matt Ryan has looked terrible with pressure in his face. Unfortunately, for Colts fans, the Cowboys apply as much pressure from their front seven as any team in the NFL.

No one will play Matt Ryan in this spot, which means there is an opportunity to gain leverage if the Colts can somehow figure out their pass-blocking up front.

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Best running back picks

Cash Games: Ezekiel Elliott, RB, Dallas Cowboys (DraftKings $8, FanDuel $12K)

Ezekiel Elliott's Cash game call comes down to a combination of things. First, Zeke's price tag remains marginal and a bargain compared to what you have to pay to acquire Jonathan Taylor. Also, you have to imagine the Cowboys are leading throughout this game, likely by multiple scores.

If that is the case, not only are the scoring opportunities a good thing for the Cowboys' backfield, but the game script remains in their favor. Lastly, Zeke looked great last week and has put his injury behind him.

Tournament: Jonathan Taylor, RB, Indianapolis Colts (DraftKings $K, FanDuel $15K)

Jonathan Taylor will likely be less-owned than usual due to the match-up with the high-profile Dallas Cowboys defense. The way to beat the Cowboys is on the ground, making Jonathan Taylor a valuable, high-end tournament option.

Wide receivers and tight ends

Cash Games: CeeDee Lamb, WR, Dallas Cowboys (DraftKings $K, FanDuel $14K)

CeeDee Lamb continues to operate as the primary pass-catcher for the Dallas Cowboys.

Lamb has had a roller-coaster season, but remember he was playing with Cooper Rush under center for several of those games. Dak Prescott knows to feed his alpha receiver. No one in the Colts' secondary can check CeeDee Lamb for 60 minutes.

Tournament: Michael Pittman Jr., WR, Indianapolis Colts (DraftKings $K, FanDuel $13K)

Michael Pittman Jr. has been underwhelming lately, resulting in his ownership dropping in the DFS circles. The Dallas Cowboys bring a daunting defense to the table, which many players will want to avoid.

The match-up is another reason DFS players avoid Michael Pittman Jr. in this spot. When all of the narratives suggest DFS players are fading a player, it provides an opportunity to take advantage and gain leverage on the field with a contrarian play.

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