Best NFL DFS Picks Sunday: Jaguars vs. Lions-December 4 | 2022 NFL Regular Season

For two teams near the bottom of the NFL for some time, the Jacksonville Jaguars vs. Detroit Lions match-up has plenty of intrigue for DFS purposes.

Best quarterback picks

Cash Games: Trevor Lawrence, QB, Jacksonville Jaguars (DraftKings $5.9K, FanDuel $7.5K)

Many in the DFS streets believe that Trevor Lawrence is one of the best plays on the slate, regardless of position. The Detroit Lions are horrific against the Fantasy QB position, and this game has shoot-out written all over it. Trust in Trevor.

Tournaments: Jared Goff, QB, Detroit Lions (Draftkings $5.3K, FanDuel $6.8K)

With many selecting Trevor Lawrence as their DFS QB, you can leverage a cheaper option with just as much upside in Jared Goff.

$1,000 No Sweat First Bet with FanDuel

Best running back picks

Cash Games: Jamaal Williams, RB, Detroit Lions (DraftKings $6K, FanDuel $7.5K)

Reports out of Detroit are that D'Andre Swift is as healthy as he has been all season long for this match-up. While that may lead some to believe Swift will have a larger workload for this one, the Lions will keep their current balance. The Lions like the physicality Jamaal Williams brings, and will continue hammering the bruising back between the tackles.

Tournament: Travis Etienne Jr., RB, Jacksonville Jaguars (DraftKings $6.4K, FanDuel $8K)

Keep an eye on the pre-game warmups, but from all accounts, Travis Etienne is full steam ahead this weekend against the Lions. Detroit have struggled to contain multi-faceted backs all season long. With Darrell Henderson Jr. still getting used to the Jaguars' playbook, Etienne should be fed heavily this week.

Wide receivers and tight ends

Cash Games: Amon-Ra St. Brown, WR, Detroit Lions ($7.1K, FanDuel $8K)

Amon-Ra is the chalk play and the Lions will have to throw the ball to keep pace in this one. The Lions don't have many pass-catchers now that they have traded away TE T.J. Hockenson. We haven't seen the ceiling performance from Amon-Ra for a while now, but I think we are getting it this weekend.

Tournament: Christian Kirk, WR, Jacksonville Jaguars (DraftKings $6.3K, FanDuel $7.5K)

Christian Kirk and Zay Jones are in play for this one. The Lions are awful against the pass, and the Jaguars pay at a fast pace of play, which means the Jaguars' receivers will have plenty of opportunities to get loose in the Lions' secondary. We know that Trevor Lawrence and Christian Kirk have a strong connection.

$1,000 No Sweat First Bet with FanDuel