Best NFL Parlay Bets for Today (+405) - Chargers vs. 49ers - Week 10 - November 13 | 2022 NFL Football Season

The Los Angeles Chargers (5-3) will take on the San Francisco 49ers (4-4) in a primetime Sunday night matchup. The Chargers bested the Atlanta Falcons 20-17 in a wild back-and-forth last Sunday.

With Los Angeles driving late in the fourth, running back Austin Ekeler fumbled with 34 seconds remaining in Falcons territory. Ekeler's fumble was recovered by Atlanta defensive lineman Ta'Quon Graham, who also coughed it up while returning the ball, leading to Chargers LT Matt Feiler falling on it.

Los Angeles QB Justin Herbert hit WR Josh Palmer for a 22-yard gain before Cameron Dicker nailed the game-ending field goal.

The 49ers had a Week 9 bye but beat up the Los Angeles Rams the week prior, 31-14. Star running back Christian McCaffrey, acquired via trade before Week 7, threw, caught, and rushed for a touchdown in the rout of their division foe. He is just the 11th player in NFL history to accomplish that feat.

Below, we'll go through the best parlay to make for Sunday's contest.

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NFL Parlay Leg #1: San Francisco 49ers ML (-335)

Let's just get the first leg out of the way with a near gimmie. The 49ers are the better team, are at home, and are trending forward. Their run-heavy approach also matches up well against a poor Chargers front seven. The time of possession and game script should favor San Francisco, potentially leading to short fields for the 49ers' offense. I like them to cover the spread, but grabbing the moneyline is the safe bet.

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NFL Parlay Leg #2: 49ers RB Christian McCaffrey Any Time Touchdown (-210)

There is a good chance that he won't score three touchdowns for a second consecutive week, but his snap count is only increasing, and the 49ers' run game should dominate the Chargers. With someone as explosive as McCaffrey, it only takes one play for him to scamper into the endzone.

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NFL Parlay Leg #3: Chargers QB Justin Herbert Over 275 Passing Yards (+148)

In a matchup that may get ugly quickly, Los Angeles will have to rely on their quarterback to get them on track. Even if LA find a way to hang with the 49ers for the entirety of the game, it should be the passing attack of Los Angeles that keeps the offense afloat.

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NFL Parlay Leg #4: Chargers WR Josh Palmer 40+ Receiving Yard (-190)

Somebody has to catch the ball for LA. Palmer is the last remaining healthy receiver for Los Angeles, who was a starter in Week 1. He was peppered last week with fellow receivers Mike Williams and Keenan Allen available. He had eight receptions on ten targets for 106 yards in the win over Atlanta.

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