Oregon Ducks vs. Colorado Buffalos Odds, Lines, Prediction, and Picks - November 5 | 2022 NCAA Regular Season

The Oregon Ducks are currently one of the hottest teams in College Football, as they have won their seventh straight contest while scoring over 40 points in every game.

The Ducks have been unstoppable offensively and are wrecking teams. They haven't been in a close game in quite some time, and I don't see this one much differently.

The Colorado Buffalos have nothing on defense that would deter the Ducks from doing whatever they want to on offense.

The betting odds and predictions are below:

TEAMS	LINE	TOTAL
Oregon Ducks	-31.5 (-110)	O 63 (-110)
Colorado Buffalos	+31.5 (-110)	U 63 (-110)

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Bo Nix is the leader of the Oregon Ducks offense. Nix has been on fire with 20 TD passes to only five interceptions. Nix causes issues for the opposition because he is an effective runner. Bo Nix has run 440 yards and found the end zone 11 times as a runner.

Bucky Irving and Noah Whittington pose a 1-2 punch as both backs average 6.4 yards per carry.

Troy Franklin leads a speedy receiving group for the Ducks, but they spread the ball around so well that the defense cannot key on any player.

The Buffalos don't offer up much offensively. If they have a chance of keeping it close, RB Deion Smith will have to have the game of his life.

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Oregon Ducks vs. Colorado Buffalos Game Details

Fixture: Oregon Ducks @ Colorado Buffalos

Date and Time: Saturday, November 5, 3 3:30 PM ET

Venue: Folsom Field, Boulder, Colorado

Oregon Ducks vs. Colorado Buffalos Best Pick:

The Colorado defense does not stand a chance in this one. Oregon will do whatever they want on offense. If the passing yardage number was larger, I would be hesitant, but at 265.5--I expect the Ducks to do enough damage through the air to eclipse the Over.

Bo Nix, 265.5 Passing Yards: Over

Oregon Ducks vs. Colorado Buffalos Final Prediction

Oregon vs. Colorado should be one of the most one-sided games this weekend. The Ducks are steamrolling all other teams, winning by multiple scores every time out.

Their offense continues to score over 40 points each week, and that has been against tougher defenses than what Colorado possess. I wouldn't be surprised if Oregon reached the mid-50s in this one. Take Oregon.

Oregon Ducks: -31.5 (-110)

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