EPL 2016-17: 5 key players ruled out of Matchday 7

#2 Harry Kane

Harry Kane was the Premier League’s top scorer last season

While De Bruyne misses out for Manchester City, Harry Kane will watch the match from the stands for Tottenham Hotspur. In the league fixture against Sunderland on September 18, Kane suffered an ankle injury while attempting a tackle shortly after scoring a goal which turned out to be the winner.

It will be interesting to see how Spurs fare against the leaders, Manchester City, without their star striker. Tottenham manager Mauricio Pochettino has confirmed that Kane will be out for over four weeks and will hopefully recover before the North London derby on November 6.