#4 Chris Guccione (Australia)
Chris Guccione met Nadal for the first and only time in the opening round at Sydney 2007. The Australian left-hander emerged victorious after his fellow southpaw retired down 5-6 in the first set.
#5 Alex Corretja (Spain)
One of only two players to have played Nadal multiple times without enduring a defeat, Alex Corretja beat his younger compatriot on clay in the opening round at Barcelona 2003.
Corretja's second meeting with Nadal was on the hardcourts of the Madrid Masters that same season, where the 19-time Grand Slam champion went down in three sets to his elder countryman.
#6 Dustin Brown (Germany)
Dustin Brown is the only other player, apart from Alex Corretja, to have played Nadal multiple times and emerged victorious on each occasion.
The German journeyman won both of his meetings against the left-handed Spaniard on grass. He dropped a total of one set during victories in the opening round at Halle in 2014 and in the second round at Wimbledon 2015.
Brown is one of only four players - Roger Federer, Gilles Muller and Novak Djokovic being the others - to have beaten Nadal multiple times on grass.
What is the foot injury that has troubled Rafael Nadal over the years? Check here