Mixed Doubles US Open Winners
| Year | Champion |
| 1969 | Margaret Court/Marty Riessen |
| 1970 | Margaret Court/Marty Riessen |
| 1971 | Billie Jean King/Owen Davidson |
| 1972 | Margaret Court/Marty Riessen |
| 1973 | Billie Jean King/Owen Davidson |
| 1974 | Pam Teeguarden/Geoff Masters |
| 1975 | Rosemary Casals/Dick Stockton |
| 1976 | Billie Jean King/Phil Dent |
| 1977 | Betty Stöve/Frew McMillan |
| 1978 | Betty Stöve/Frew McMillan |
| 1979 | Greer Stevens/Bob Hewitt |
| 1980 | Wendy Turnbull/Marty Riessen |
| 1981 | Anne Smith/Kevin Curren |
| 1982 | Anne Smith/Kevin Curren |
| 1983 | Elizabeth Sayers Smylie/John Fitzgerald |
| 1984 | Manuela Maleeva/Tom Gullikson |
| 1985 | Martina Navratilova/Heinz Günthardt |
| 1986 | Raffaella Reggi/Sergio Casal |
| 1987 | Martina Navratilova/Emilio Sánchez Vicario |
| 1988 | Jana Novotná/Jim Pugh |
| 1989 | Robin White/Shelby Cannon |
| 1990 | Elizabeth Sayers Smylie/Todd Woodbridge |
| 1991 | Manon Bollegraf/Tom Nijssen |
| 1992 | Nicole Provis/Mark Woodforde |
| 1993 | Helena Suková/Todd Woodbridge |
| 1994 | Elna Reinach/Patrick Galbraith |
| 1995 | Meredith McGrath/Matt Lucena |
| 1996 | Lisa Raymond/Patrick Galbraith |
| 1997 | Manon Bollegraf/Rick Leach |
| 1998 | Serena Williams/Max Mirnyi |
| 1999 | Ai Sugiyama/Mahesh Bhupathi |
| 2000 | Arantxa Sánchez Vicario/Jared Palmer |
| 2001 | Rennae Stubbs/Todd Woodbridge |
| 2002 | Lisa Raymond/Mike Bryan |
| 2003 | Katarina Srebotnik/Bob Bryan |
| 2004 | Vera Zvonareva/Bob Bryan |
| 2005 | Daniela Hantuchová/Mahesh Bhupathi |
| 2006 | Martina Navratilova/Bob Bryan |
| 2007 | Victoria Azarenka/Max Mirnyi |
| 2008 | Cara Black/Leander Paes |
| 2009 | Carly Gullickson/Travis Parrot |
| 2010 | Liezel Huber/Bob Bryan |
| 2011 | Melanie Oudin/Jack Sock |
| 2012 | Ekaterina Makarova/Bruno Soares |
| 2013 | Andrea Hlaváčková/Max Mirnyi |
| 2014 | Sania Mirza/Bruno Soares |
| 2015 | Martina Hingis/Leander Paes |
| 2016 | Laura Siegemund/Mate Pavić |
| 2017 | Martina Hingis/Jamie Murray |
| 2018 | Bethanie Mattek-Sands/Jamie Murray |
| 2019 | Bethanie Mattek - Sands/ Jamie Murray |
| 2021 | Desirae Krawczyk / Joe Sallisbury |
| 2022 | Storm Sanders / John Peers |
| 2023 | Anna Danilina / Harri Heliövaara |
| 2024 | Sara Errani / Andrea Vavassori |
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