Who is leaving General Hospital in 2025? All comings and goings explored

The current storylines on General Hospital spotlight intense family dynamics and medical crises, leaving Port Charles residents grappling with tough choices. Willow's choice to take charge of Michael's care creates tension with Carly, and Drew's involvement sparks more conflict.

At the same time, Tracy's actions have landed her in legal trouble, with her arrest intensifying the custody battle over Willow's children. Meanwhile, old rivalries and alliances shift dramatically. Jason's decision to put Monica before Sonny creates a major divide and Ava's efforts to get custody of Avery add more tension to the family feud.

As secrets come out, relationships are being tested, and everyone in Port Charles is preparing for the emotional fallout from all these conflicts. In 2025, General Hospital confirmed Chad Duell's exit as Michael Corinthos, marking a significant shift in the Corinthos family storyline.

Meanwhile, temporary exits include Monica Quartermaine, Charlotte Cassadine, and Valentin Cassadine. As the show has not confirmed their permanent departures, fans are left curious about their eventual returns and the impact on ongoing narratives.

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All confirmed entries and exits on General Hospital in 2025

Return

1) Lydia Look as Selina Wu

Lydia Look as Selina Wu in General Hospital (Image via YouTube/General Hospital)

Lydia Look is set to make a dramatic comeback as Selina Wu on General Hospital this week, marking her first appearance in nearly a year. Selina was last seen in March 2024, when she gave Curtis a serious warning at The Savoy before disappearing. Her return promises to stir up chaos, especially with Cody and Brad drawn into her underworld dealings.

Cody's desperation to fund a risky bet leads him to Selina's illegal gambling operation, reigniting her influence in Port Charles. At the same time, Brad, who's been trying to stay away from his aunt and her criminal world, gets dragged back into her schemes.

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Exits

1) Chad Duell as Michael Corinthos

After playing Michael Corinthos on General Hospital for more than 14 years, Chad Duell has decided to leave the role. In November 2024, he announced his departure on Instagram, saying:

“This wasn’t an easy decision, but it feels like the right time in my life.”

He expressed gratitude to the cast and crew, calling them "family."

On the Daily Drama podcast, Duell explained his decision, mentioning personal reasons like his father's death and wanting to spend more time with his partner, Luana Lucci, and their son, Dawson. While the door remains open for a return, Duell is focused on personal growth and new opportunities, teasing upcoming projects in 2025.

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2) Leslie Charleson as Monica Quartermaine

Leslie Charleson, who played Monica Quartermaine in General Hospital for more than 40 years, passed away on January 12, 2025. The show has not confirmed if the role will be recast, as Monica hasn't appeared since Charleson took a break in December 2023.

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3) The father-daughter duo

James Patrick Stuart and Scarlett Fernandez, who play Valentin Cassadine and his daughter Charlotte, have been temporarily taken off General Hospital. In recent episodes of the show, Lulu visits Prague to get her daughter, Charlotte, back. However, she had to return empty hands.

But fans can look forward to seeing them again later this year when Anna (played by Finola Hughes) tries to save Valentin. As Valentin's troubled past keeps affecting him, Charlotte's role in his story will also evolve.

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Fans of the show can watch new episodes on ABC and Hulu.