#3 Negative: Roman Reigns relinquishment
Roman Reigns announced the devastating news in October 2018 that he had to relinquish the Universal Championship after being diagnosed with leukemia.
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At the time, the four-time WrestleMania main-eventer was due to defend the title against Braun Strowman and Brock Lesnar in a Triple Threat match at Crown Jewel in Saudi Arabia, so WWE decided to book Strowman vs. Lesnar in a one-on-one match for the vacant title instead.
Thankfully, four months after Reigns’ announcement, he returned to WWE in February 2019 and revealed that his leukemia was in remission.
He has since returned to in-ring action, taking part in multiple Shield reunions before defeating Drew McIntyre at WrestleMania 35, while he is currently involved in rivalries on both Raw and SmackDown Live with Shane McMahon and Elias.
Unlike Finn Balor, who finally received opportunities at the Universal Championship after he was forced to relinquish it, Reigns is yet to be given a shot at the title that he never officially lost.