#1 Joining forces with Andrade
If you can't beat 'em, join 'em. This has been a very common occurrence in WWE over the years. It has happened with the Wyatt Family on multiple occasions, while Shawn Michaels was forced to work for JBL to support his family at the end of 2008.
The two scenarios mentioned could merge and form one of the more intriguing possibilities for Rey Mysterio. He could join Andrade and Zelina Vega, forming one hell of a team. Whether he is just a manager or a tag team partner, Mysterio would do wonders in this role.
He did say in the interview, that he has to support his family. This would then mean to do just that, hanging on the impressive success coming Andrade's way. Mysterio would not necessarily turn heel, he could just be a reluctant babyface. It would form one hell of a dynamic between two performers who have tremendous chemistry together.
This would ultimately lead to the Master of the 619 breaking free and becoming his own man again, going on a final run on his own or putting over Andrade one last time.
Whatever happens with Rey Mysterio, it seems intriguing. Hopefully, we see more involvement with Andrade, simply because the pair of them are tremendous together.
This seems likely to be the final stretch of Mysterio's unbelievable career, so WWE must make it count.