#1. AEW star CM Punk defeated John Cena
CM Punk is the second entry on this list to have defeated John Cena multiple times in singles action. The Best in the World went one-on-one with The Leader of the Cenation 25 times between 2009 and 2013.
Punk lost to Cena twice in a row in November and December 2009. They squared off again in June 2010 and January 2011, but both matches ended in no contest. A week after losing another bout to Cena in February 2011, Punk finally scored his first victory over the 16-time World Champion on Monday Night RAW.
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In the following years, The Best in the World defeated Cena in four more matches. He also suffered eight losses to The Leader of the Cenation, while seven bouts ended in a draw.
Punk left WWE in 2014. He then announced his retirement from pro wrestling. Nonetheless, he returned to the ring earlier this year to join AEW. The 43-year-old made his in-ring debut at the All Out pay-per-view, defeating Darby Allin. He has competed in four more matches ever since and is still undefeated.