#1 - Rey Mysterio vs Kurt Angle vs Randy Orton - World Heavyweight Championship match
Rey Mysterio won the 2006 Royal Rumble and thus received a World Heavyweight Championship match at WrestleMania 22 as mentioned previously. He faced Olympic gold medalist Kurt Angle and the youngest World Heavyweight Champion in WWE history Randy Orton for the title in a triple threat match. This match was undoubtedly the best triple threat World Heavyweight Championship match ever in the history of WrestleMania.
The three wrestlers gave it their all to beat one another. In the end, Mysterio fought all the odds and delivered a 619 on Randy Orton. It was followed by the West Coast Pop and Mysterio subsequently pinned Orton. Mysterio won the match and his first ever World Championship in the WWE.
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Rey Mysterio held the Championship for 112 days and was one of the few cruiserweight wrestlers to win the World Championship in the WWE.