#2 Shawn Michaels vs Eddie Guerrero
Court Bauer, a former WWE writer, once talked on his show about plans for Eddie Guerrero at WrestleMania. He recalled that the writing team had a call with Vince McMahon, around 2 days before Eddie died. Bruce Prichard originally pitched the idea of pitting Shawn Michaels and Eddie Guerrero against each other at WrestleMania 22.
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Reportedly, Vince absolutely loved the idea of having this match at The Grandest Stage Of Them All. The match was going to be positioned as the annual WrestleMania show-stealer between a babyface Michaels and a heel Eddie. Elaborate plans were made regarding the video packages that WWE could put out on the road to 'Mania.
Eddie's untimely death changed everything in a split second. Michaels ended up wrestling Vince himself in a street fight at WrestleMania 22. It's also worth noting that Rey Mysterio probably wouldn't have won the World Title if Eddie hadn't died in November.