#2 Lita
Without Lita there would have been no Trish Stratus, and vice versa. At least not in the way that we know them today. Their rivalry is tremendously underrated and should really go down as one of the greatest in wrestling history, male or female.
Lita got into WWE at around the same time as Trish did and really rose to prominence as the third member of Team Extreme alongside The Hardy Boyz. It soon became apparent that Lita was capable of much more than being a third wheel.
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Nowadays the women's division is full of unique women who break the mould. Lita was one of the first women to do that and proved that females could reach the top of the company without being blonde supermodel types.